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Fatigue crack initiation of magnesium alloys under elastic stress amplitudes: A review

B. J. WANG, D. K. XU, S. D. WANG, E. H. HAN

《机械工程前沿（英文）》 2019年第14卷第1期页码 113-127 doi: 10.1007/s11465-018-0482-1

摘要： The most advantageous property of magnesium (Mg) alloys is their density, which is lower compared with traditional metallic materials. Mg alloys, considered the lightest metallic structural material among others, have great potential for applications as secondary load components in the transportation and aerospace industries. The fatigue evaluation of Mg alloys under elastic stress amplitudes is very important in ensuring their service safety and reliability. Given their hexagonal close packed structure, the fatigue crack initiation of Mg and its alloys is closely related to the deformation mechanisms of twinning and basal slips. However, for Mg alloys with shrinkage porosities and inclusions, fatigue cracks will preferentially initiate at these defects, remarkably reducing the fatigue lifetime. In this paper, some fundamental aspects about the fatigue crack initiation mechanisms of Mg alloys are reviewed, including the 3 followings: 1) Fatigue crack initiation of as-cast Mg alloys, 2) influence of microstructure on fatigue crack initiation of wrought Mg alloys, and 3) the effect of heat treatment on fatigue initiation mechanisms. Moreover, some unresolved issues and future target on the fatigue crack initiation mechanism of Mg alloys are also described.

关键词： Mg alloys fatigue behavior microstructure crack initiation deformation mechanism

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Hierarchical approach for fatigue cracking performance evaluation in asphalt pavements

Ibrahim ONIFADE, Yared DINEGDAE, Björn BIRGISSON

《结构与土木工程前沿（英文）》 2017年第11卷第3期页码 257-269 doi: 10.1007/s11709-017-0410-1

摘要： In this paper, a hierarchical approach is proposed for the evaluation of fatigue cracking in asphalt concrete pavements considering three different levels of complexities in the representation of the material behaviour, design parameters characterization and the determination of the pavement response as well as damage computation. Based on the developed hierarchical approach, three damage computation levels are identified and proposed. The levels of fatigue damage analysis provides pavement engineers a variety of tools that can be used for pavement analysis depending on the availability of data, required level of prediction accuracy and computational power at their disposal. The hierarchical approach also provides a systematic approach for the understanding of the fundamental mechanisms of pavement deterioration, the elimination of the empiricism associated with pavement design today and the transition towards the use of sound principles of mechanics in pavement analysis and design.

关键词： fatigue cracking energy based crack initiation mechanistic approach pavement analysis

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Cracking evolution behaviors of lightweight materials based on

Y. Luo, S. C. Wu, Y. N. Hu, Y. N. Fu

《机械工程前沿（英文）》 2018年第13卷第4期页码 461-481 doi: 10.1007/s11465-018-0481-2

摘要：

Damage accumulation and failure behaviors are crucial concerns during the design and service of a critical component, leading researchers and engineers to thoroughly identifying the crack evolution. Third-generation synchrotron radiation X-ray computed microtomography can be used to detect the inner damage evolution of a large-density material or component. This paper provides a brief review of studying the crack initiation and propagation inside lightweight materials with advanced synchrotron three-dimensional (3D) X-ray imaging, such as aluminum materials. Various damage modes under both static and dynamic loading are elucidated for pure aluminum, aluminum alloy matrix, aluminum alloy metal matrix composite, and aluminum alloy welded joint. For aluminum alloy matrix, metallurgical defects (porosity, void, inclusion, precipitate, etc.) or artificial defects (notch, scratch, pit, etc.) strongly affect the crack initiation and propagation. For aluminum alloy metal matrix composites, the fracture occurs either from the particle debonding or voids at the particle/matrix interface, and the void evolution is closely related with fatigued cycles. For the hybrid laser welded aluminum alloy, fatigue cracks usually initiate from gas pores located at the surface or sub-surface and gradually propagate to a quarter ellipse or a typical semi-ellipse profile.

关键词： fatigue crack initiation and growth fatigue damage mechanism damage tolerance defect characterization laser welded aluminum alloys

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城市高架桥爆破拆除起爆网路可靠性研究

吴新霞,赵根,谢先启

《中国工程科学》 2014年第16卷第11期页码 72-77

摘要：

本文针对城市高架桥爆破拆除的长距离、长延时，目前只能采用非电起爆网路进行起爆的现状，研究了多发并联起爆网路的接力点雷管延期特性，提出了并联后的接力点起爆时间期望值的简易计算公式。针对不同规模的非电起爆网路提出了相应的可靠度标准，研发了既可保证高架桥倾倒过程不发生侧翻又能提高接力点起爆可靠度并可无限分段的复式交叉接力起爆网路，并推导了其起爆可靠度计算公式。相关成果为高架桥拆除爆破起爆网路设计提供了科学依据。

关键词：高架桥拆除爆破起爆网路可靠性

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Dynamic crack propagation in plates weakened by inclined cracks: an investigation based on peridynamics

A. SHAFIEI

《结构与土木工程前沿（英文）》 2018年第12卷第4期页码 527-535 doi: 10.1007/s11709-018-0450-1

摘要： Peridynamics is a theory in solid mechanics that uses integral equations instead of partial differential equations as governing equations. It can be applied to fracture problems in contrast to the approach of fracture mechanics. In this paper by using peridynamics, the crack path for inclined crack under dynamic loading were investigated. The peridynamics solution for this problem represents the main features of dynamic crack propagation such as crack bifurcation. The problem is solved for various angles and different stress values. In addition, the influence of geometry on inclined crack growth is studied. The results are compared with molecular dynamic solutions that seem to show reasonable agreement in branching position and time.

关键词： peridynamics inclined crack dynamic fracture crack branching

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hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation

《医学前沿（英文）》 2023年第17卷第3期页码 476-492 doi: 10.1007/s11684-022-0966-6

摘要： tRNA-derived small RNAs (tsRNAs) are novel non-coding RNAs that are involved in the occurrence and progression of diverse diseases. However, their exact presence and function in hepatocellular carcinoma (HCC) remain unclear. Here, differentially expressed tsRNAs in HCC were profiled. A novel tsRNA, tRNA^Gln-TTG derived 5′-tiRNA-Gln, is significantly downregulated, and its expression level is correlated with progression in patients. In HCC cells, 5′-tiRNA-Gln overexpression impaired the proliferation, migration, and invasion in vitro and in vivo, while 5′-tiRNA-Gln knockdown yielded opposite results. 5′-tiRNA-Gln exerted its function by binding eukaryotic initiation factor 4A-I (EIF4A1), which unwinds complex RNA secondary structures during translation initiation, causing the partial inhibition of translation. The suppressed downregulated proteins include ARAF, MEK1/2 and STAT3, causing the impaired signaling pathway related to HCC progression. Furthermore, based on the construction of a mutant 5′-tiRNA-Gln, the sequence of forming intramolecular G-quadruplex structure is crucial for 5′-tiRNA-Gln to strongly bind EIF4A1 and repress translation. Clinically, 5′-tiRNA-Gln expression level is negatively correlated with ARAF, MEK1/2, and STAT3 in HCC tissues. Collectively, these findings reveal that 5′-tiRNA-Gln interacts with EIF4A1 to reduce related mRNA binding through the intramolecular G-quadruplex structure, and this process partially inhibits translation and HCC progression.

关键词： EIF4A1 G-quadruplex hepatocellular carcinoma tRNA-derived small RNA translation initiation

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Liquid metal material genome: Initiation of a new research track towards discovery of advanced energy

Lei WANG, Jing LIU

《能源前沿（英文）》 2013年第7卷第3期页码 317-332 doi: 10.1007/s11708-013-0271-9

摘要： As the basis of modern industry, the roles materials play are becoming increasingly vital in this day and age. With many superior physical properties over conventional fluids, the low melting point liquid metal material, especially room-temperature liquid metal, is recently found to be uniquely useful in a wide variety of emerging areas from energy, electronics to medical sciences. However, with the coming enormous utilization of such materials, serious issues also arise which urgently need to be addressed. A biggest concern to impede the large scale application of room-temperature liquid metal technologies is that there is currently a strong shortage of the materials and species available to meet the tough requirements such as cost, melting point, electrical and thermal conductivity, etc. Inspired by the Material Genome Initiative as issued in 2011 by the United States of America, a more specific and focused project initiative was proposed in this paper—the liquid metal material genome aimed to discover advanced new functional alloys with low melting point so as to fulfill various increasing needs. The basic schemes and road map for this new research program, which is expected to have a worldwide significance, were outlined. The theoretical strategies and experimental methods in the research and development of liquid metal material genome were introduced. Particularly, the calculation of phase diagram (CALPHAD) approach as a highly effective way for material design was discussed. Further, the first-principles (FP) calculation was suggested to combine with the statistical thermodynamics to calculate the thermodynamic functions so as to enrich the CALPHAD database of liquid metals. When the experimental data are too scarce to perform a regular treatment, the combination of FP calculation, cluster variation method (CVM) or molecular dynamics (MD), and CALPHAD, referred to as the mixed FP-CVM-CALPHAD method can be a promising way to solve the problem. Except for the theoretical strategies, several parallel processing experimental methods were also analyzed, which can help improve the efficiency of finding new liquid metal materials and reducing the cost. The liquid metal material genome proposal as initiated in this paper will accelerate the process of finding and utilization of new functional materials.

关键词： liquid metal material genome energy material material discovery advanced material room-temperature liquid alloy thermodynamics phase diagram

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Peridynamics versus XFEM: a comparative study for quasi-static crack problems

Jinhai ZHAO, Hesheng TANG, Songtao XUE

《结构与土木工程前沿（英文）》 2018年第12卷第4期页码 548-557 doi: 10.1007/s11709-017-0434-6

摘要： Peridynamics (PD) is a nonlocal continuum theory based on integro-differential equations without spatial derivatives. The fracture criterion is implicitly incorporated in the PD theory and fracture is a natural outcome of the simulation. However, capturing of complex mixed-mode crack patterns has been proven to be difficult with PD. On the other hand, the extended finite element method (XFEM) is one of the most popular methods for fracture which allows crack propagation with minimal remeshing. It requires a fracture criterion which is independent of the underlying discretization though a certain refinement is needed in order to obtain suitable results. This article presents a comparative study between XFEM and PD. Therefore, two examples are studied. The first example is crack propagation in a double notched specimen under uniaxial tension with different crack spacings in loading direction. The second example is the specimens with two center cracks. The results show that PD as well as XFEM are well suited to capture this type of behaviour.

关键词： XFEM peridynamic bilateral crack parallel double cracks nonlocal theory

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Correlation between tension softening relation and crack extension resistance in concrete

Xiufang ZHANG , Shilang XU ,

《结构与土木工程前沿（英文）》 2009年第3卷第3期页码 323-329 doi: 10.1007/s11709-009-0041-2

摘要： Changes of the material fracture energy consumption with crack propagation can be described by a crack extension resistance curve, one of the fundamental fracture criteria in crack mechanics. Recently, experimental observation of the fracture behavior in concrete was used to develop a new fracture criterion, the crack extension resistance curve, to analyze crack propagation during the entire concrete fracture process. The variation of the crack extension resistance is mainly associated with the energy consumption in the fracture process zone ahead of the stress-free crack tip. The crack extension resistance is then a function of the softening curve, which is a basic mechanical property in the fracture process zone. The relationship between the softening curve and the crack extension resistance curve is then analyzed based on results of three-point bending beams tests. The results indicate that the characteristic points of the crack extension resistance curve is closely related to the characteristic point on used tension softening curve.

关键词： concrete fracture process zone crack extension G_R resistance tension softening curve

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Breast cancer-associated fibroblasts: their roles in tumor initiation, progression and clinical applications

null

《医学前沿（英文）》 2016年第10卷第1期页码 33-40 doi: 10.1007/s11684-016-0431-5

摘要：

Breast cancer is the most common malignant tumor in women, and the incidence of this disease has increased in recent years because of changes in diet, living environment, gestational age, and other unknown factors. Previous studies focused on cancer cells, but an increasing number of recent studies have analyzed the contribution of cancer microenvironment to the initiation and progression of breast cancer. Cancer-associated fibroblasts (CAFs), the most abundant cells in tumor stroma, secrete various active biomolecules, including extracellular matrix components, growth factors, cytokines, proteases, and hormones. CAFs not only facilitate the initiation, growth, angiogenesis, invasion, and metastasis of cancer but also serve as biomarkers in the clinical diagnosis, therapy, and prognosis of breast cancer. In this article, we reviewed the literature and summarized the research findings on CAFs in breast cancer.

关键词： cancer-associated fibroblast breast cancer progression prognosis

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Fracture resistance on aggregate bridging crack in concrete

ZHANG Xiufang, XU Shilang

《结构与土木工程前沿（英文）》 2007年第1卷第1期页码 63-70 doi: 10.1007/s11709-007-0006-2

摘要： Fracture toughening exhibited in quasi-brittle materials such as concrete is often mainly related to the action of aggregate bridging, which leads to the presence of a fracture process zone ahead of stress-free cracks in such materials. In this investigation, the fracture resistance induced by aggregate bridging, denoted by GI-bridging, is the primary focus. In order to quantitatively determine it, a general analytical formula is firstly developed, based on the definition of fracture energy by Hillerborg. After this, we further present the calculated procedures of determining this fracture resistance from the recorded load vs. crack opening displacement curve. Then, both numerical simulations and fracture experiments are performed on concrete three-point bending beams. Utilizing the obtained load against crack opening displacement curve, the value of G at any crack extension as well as the change of G with the crack extension is examined. It is found that G will firstly increase with the development of crack and then stay constant once the initial crack tip opening displacement reaches the characteristic crack opening displacement w0. The effects of material strength and specimen depth on this fracture resistance are also investigated. The results reveal that the values of G of different specimens at any crack propagation are strongly associated with the values of fracture energy of specimens. If the values of fracture energy between different specimens are comparable, the differences between G are ignored. Instead, if values of fracture energy are different, the G will be different. This shows that for specimens with different strengths, G will change greatly whereas for specimens that are different in depth, whether GI-bridging exhibits size effect depends on whether the fracture energy of specimens considered in the calculation of G is assumed to be a size-dependent material parameter.

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Stability and dynamics of rotor system with 45° slant crack on shaft

Yanli LIN, Xiaohui SI, Fulei CHU

《机械工程前沿（英文）》 2011年第6卷第2期页码 203-213 doi: 10.1007/s11465-011-0131-4

摘要：

Crack on a shaft is one of the common damages in a rotor system. In this paper, transverse vibrations are calculated to compare the influences of transverse crack and slant crack on the rotor system. Results show that the vibration amplitude of the rotor system with a 45° slant crack on the shaft is larger than that with a transverse crack when the two types of crack have the same depth and the rotor system runs in the same condition. Stability and dynamic characteristics of the rotor system with a 45° slant crack on the shaft under torsional excitation are analyzed by considering opening and closing of the crack. It is shown that the instability of the transverse vibration of the rotor system increases with increasing difference between the bending stiffness in two main directions, and the vibration is stable when the two bending stiffness are identical. The spectrum analysis of the steady-state response reveals that the gravity and the eccentricity produce different frequency components, and when the two bending stiffness are identical, the multiple frequency components of the torsional excitation disappear. Further investigation shows that the vibration amplitudes in combined frequencies increase rapidly in transversal, torsional, and axial vibration with increasing slant crack depth. The results are helpful for the understanding the dynamic behavior of a rotor system with a slant crack on a shaft and can be used for the detection of the slant crack on a shaft.

关键词： rotor dynamics slant crack stability torsional excitation open and close

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Study on the cohesion and adhesion of hot-poured crack sealants

Meng GUO, Yiqiu TAN, Xuesong DU, Zhaofeng LV

《结构与土木工程前沿（英文）》 2017年第11卷第3期页码 353-359 doi: 10.1007/s11709-017-0400-3

摘要： Filling crack sealant is a main method to repair cracking of pavement. The cohesion and adhesion of crack sealant directly determine its service performance and durability. However, the competitive mechanism of cohesion and adhesion failure modes is not clear currently. This research proposed two methods to evaluate cohesion and adhesion of crack sealant, and analyzed the influence of temperature on cohesion and adhesion. The effect of moisture on low-temperature performance of crack sealant was also be evaluated by conducting a soaking test. Results show that with the decrease of temperature, the cohesion force of crack sealant increases significantly, while the adhesion force changes little. There is a critical temperature at which the cohesion force equals the adhesion force. When the temperature is higher, the adhesion force will be greater than cohesion force, and the cohesion failure will happen more easily. In contrast, the adhesion failure will happen more easily when the temperature is lower than the critical value. Soaking in 25 °C water for 24–48 hours will slightly improve the low-temperature tension performance of crack sealant. However, soaking in 60 °C water for 24 hours will decrease the failure energy of low-temperature tension and damage the durability of crack sealant.

关键词： crack sealant concrete pavement cohesion adhesion moisture damage

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Feasibility of crack free reinforced concrete bridge deck from materials composition perspective: a state

Mahdi AREZOUMANDI

《结构与土木工程前沿（英文）》 2015年第9卷第1期页码 91-103 doi: 10.1007/s11709-015-0274-1

摘要： Early age cracking on bridge deck has been the subject of many studies for years. Cracking is a major concern because it leads to premature deterioration of structures. Millions of dollars spent to repair the cracked bridge decks each year. To design an appropriate mixture for crack free bridge deck, it is important to study previous researches. This paper presents a comprehensive literature review of the performance of different materials compositions as well as methods have been used to reduce and control bridge deck cracks. Different material compositions and methods are discussed in terms of their performances as well as advantages and disadvantages.

关键词： bridge deck crack fiber shrinkage shrinkage reducing admixture

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Concurrent fatigue crack growth simulation using extended finite element method

Zizi LU, Yongming LIU,

《结构与土木工程前沿（英文）》 2010年第4卷第3期页码 339-347 doi: 10.1007/s11709-010-0078-2

摘要： In this paper, a concurrent simulation framework for fatigue crack growth analysis is proposed using a novel small time scale model for fatigue mechanism analysis and the extended finite element method (X-FEM) for fatigue crack growth simulation. The proposed small time scale fatigue model does not require the cycle counting as those using the classical fatigue analysis methods and can be performed concurrently with structural/mechanical analysis. The X-FEM greatly facilitates crack growth simulation without remeshing requirements ahead of the crack tip as in the classical finite element method. The basic concept and theory of X-FEM was briefly introduced and numerical predictions of stress intensity factors are verified with reference solutions under both uniaxial and multiaxial loadings. The small time scale fatigue model is integrated into the numerical simulation algorithm for concurrent fatigue crack growth analysis. Model predictions are compared with available experimental observations for model validation.

关键词： small time scale model extended finite element method (X-FEM) crack growth multiaxial